Wyandot, sometimes known as Hurons, Wyandot, or Wyandotte, formerly inhabited southern Ontario. They named themselves "Wendat," which eventually evolved into "Wyandot". In the years preceding the European settlement, they were expelled from their territory by the Iroquois Confederacy. They established their primary settlements in Wyandot, Marion, and Crawford Counties, but also inhabited the entirety of northern Ohio and Ross County to the south. They were a confederacy of numerous Wyandot-speaking peoples who had a unique relationship with the Shawnee. Their ties with other nations in Ohio shifted with the times. They were French allies until approximately 1740, when British traders entered Ohio Country.

During the American Revolution (1775-83), Wyandot fought with the British against the Americans. In 1782, Colonel William Crawford launched an expedition against the Wyandot settlement of Upper Sandusky where he was captured and executed. In 1787 the Northwest Territory was declared off-limits to colonizers and was home to the Anishinaabe and other Indigenous peoples who had been there for centuries. In addition to those who had been displaced from their own homelands, due to the on-going displacement of indigenous peoples' treaties often included Tribes that were refugees in the Anishinaabe Nation, like the Wyandot who had been pushed west in the 1640's.

As a result of the Battle of Fallen Timbers. "The Indians" signed the Treaty of Greenville on August 3rd, 1795, which ceded strategic areas, including Detroit, and control of most of the river crossings in the Old Northwest Territory to the United States. In Michigan, Huron Potawatomi was involved in 11 different land treaties, the Treaty of Detroit resulted in the most significant reduction of land for the Band.  

In Detroit alone, the Potawatomi, Chippewa, Ottawa, and Wyandots ceded eight million acres to the U.S. Government after the signing of The

Treaty of Detroit on November 17th, 1807. In 1842, the Indian Removal Policy required the Wyandots to relinquish their claims to their Upper Sandusky reservation and sell their land under fair market value. In 1843, the United States government relocated the Wyandot to the reservation that is now, Wyandotte County, Kansas. Following the end of the revolutionary war, Ohio Wyandot were relocated to Oklahoma.

Today, they have four recognized bands in the United States and Canada: Wyandotte Nation (Oklahoma), Huron-Wendat Nation (Wendake, Quebec), Wyandot Nation of Anderdon (Michigan), and Wyandot Nation (Kansas).